A Beginner’s Guide to Weight Loss Medications in the UK
- yourmedicals
- May 23
- 2 min read
For many individuals dealing with obesity or ongoing weight gain, diet and activity on its own is not always going to be enough. Fortunately, there are now a number of approved weight loss medications in the UK. If you are new to weight loss medications, you can be able to make a more informed decision by better understanding the different types available to you, such as Alli capsules and weight loss medication injections.

What are Weight Loss Medications?
Weight loss medications are meant to support people who struggle to lose weight using lifestyle changes only. Weight loss medications are usually targeted for people with a BMI of 30 or more, or 27 or more if you have other health problems related to your weight, such as type 2 diabetes or high blood pressure.
These medications are not wonder pills, and will, on their own, not help you to lose weight. Rather, they are meant to help you in your weight loss journey alongside a healthy diet and regular physical exercise.
What Are Alli Capsules?
Alli (with orlistat) is one of the best-known over-the-counter weight loss supplements in the UK. Alli inhibits the absorption of fat from your digestive system. It stops around 25% of the fat you take in from being absorbed and it is eliminated naturally from the body.
Alli capsules are licensed for use in adults with a body mass index (BMI) of 28 or more and as part of a diet with reduced calories and low-fat consumption. It is available without a prescription in the pharmacy. To assess if you are eligible and to ensure you understand how to use it, you should speak to a pharmacist or GP.
The most common side effects are gastrointestinal disorders with oily stools, flatulence, or an urgent need to use the toilet, with an excess of fat in the meal.
What About Weight Loss Medication Injections?
The recent increase in prescription weight loss medication injection use has grown considerably recently with people using drugs like semaglutide, marketed as Wegovy and Ozempic (the latter is primarily for Type 2 diabetes). The usual injection frequency is once a week. The active ingredient in these injections works by mimicking one of the hormones that target sites of the brain that tell you if you are hungry or full.
So you will feel full sooner or with less food consumed (that is what the weight loss drug companies want) and less hunger.
Clinical trials have shown impressive results, with some patients losing over 10–15% of their body weight in a year. However, injections can come with side effects, including nausea, constipation, and, in rare cases, more serious complications.
These are prescription-only medications and must be prescribed by a healthcare provider after a full health assessment.
Which Option is Right for You?
Choosing between Alli capsules and a weight loss medication injection depends on your health profile, weight loss goals, and personal preferences. Alli may suit those looking for a non-prescription aid with a straightforward mechanism. Injections, though more powerful, are suited for those who need more intensive support and are comfortable with regular self-injection.
As always, speak to your GP or a qualified weight management specialist before beginning any medical weight loss programme.

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